Infrastructure

The laboratories are fully equipped with state-of-the-art technology – including those of neurology – that have a highly complex infrastructure for the care of neurological patients.

Below are specifications of the laboratories and areas available for experimental and clinical research activities.

Laboratories

*Center For Imaging Sciences and Medical Physics (CCIFM): brings together in a multiprofessional and interdisciplinary way the areas of Medicine, Nursing, Biology, Medical Physics, and Biomedical Informatics, integrating human resources and infrastructure to promote, improve, and coordinate undergraduate, graduate, and extracurricular teaching, carry out scientific research and offer extension services to the community in the area of medical images.

*Laboratory of Applied and Experimental Neurology (LAEN): functionally divided into sections of Morphology, Neuroimmunology, and Neurogenetics (Prof. Wilson Marques Jr.) and Experimental Epilepsy (Prof. João Leite), the Lab has a specific area for animals experiment; D-Wave to screening for mutations and polymorphisms; a state-of-the-art DNA sequencer, allocated to the Molecular Biology Laboratory, which recently created a bioinformatics area for the analysis of new generation sequencing and became a satellite Laboratory of the Center for Genomic Medicine (CMG) and, also, a multi-user Laboratory.

*Cerebrospinal fluid laboratory (LLCR): (Prof. Osvaldo Takayanagui) the Lab is connected with other institutional laboratories for the diagnostics for HTLV-I, herpes viruses, and others at the molecular level.

*Epilepsy Research Laboratory (LIE): under the Coordination of Prof. João Leite, the Lab performs several histochemical protocols and has a fully digitized microscopic analysis system for neuropathological studies.

*Epilepsy Surgery Center (CIREP): under the responsibility of Prof. Américo Sakamoto, the Lab acts as a Regulatory Center for epilepsy surgeries throughout the country. It relies on specific outpatient clinics for the care of adults, children, and adolescents. It was chosen by the Ministry of Health to be the advisory body for this type of surgery in the National Center for High Complexity Regulation. It performs video-EEG monitoring, pre-surgical evaluation of epilepsy, and a ketogenic diet.

*Neuroimaging Laboratory: under the responsibility of Profs. Antônio Carlos dos Santos and João Leite, the Lab is installed at the Center for image Sciences and Medical Physics of the HCFMRP.

*Laboratory of Vascular Neurology and Neurological Emergencies: it is located in the Emergency Unit of HCFMRP-USP, under the responsibility of Prof. Octávio Pontes (https://neurovascular.fmrp.usp.br/).

*Laboratory of Teaching and Research of Occupational Therapy in Childhood and Adolescence (LEPTOI): under the responsibility of Prof. Luzia Pfeifer, it develops actions and research projects, teaching, and extension that aim to integrate clinical and social aspects from two central lines of research: professional training and occupational performance of children and adolescents in different contexts.

* FMRP/USP Multi-User Equipment and Services Center (CEMU): it relies on various devices and services, including images and microscopes, flow cytometers, protein chemistry, DNA extraction, sequencing, and amplification, among others (https://emu.fmrp.usp.br/).

Hospital Complex

For the accomplishment of research projects, different labs are available, ranging from the neurophysiologic analysis to molecular biology; vivarium to work with animals; access to the patient from the Health Complex of the HCFMRP-FMRP/USP/FAEPA (https://site.hcrp.usp.br/complexo-de-saude/), consisting of the HCFMRP and the Emergency Unit, the four hospitals (Centro Estadual de Referência da Saúde da Mulher, Hospital Estadual de Américo Brasiliense, Hospital Estadual de Ribeirão Preto e Hospital Estadual de Serrana), Blood Center, and two Rehabilitation Centers (CER and CIR). FMRP, HCFMRP, and FAEPA, through an agreement with the City Hall, operate in the School Health Center and the Family Health Program of the Ministry of Health, with ten Family Health Centers installed in the West District of Ribeirão Preto.

Libraries

The Central Library of the campus of Ribeirão Preto-USP (BCRP) and the other libraries of USP are administered by the USP Agency for Academic Information Management (AGUIA).

The BCRP collection consists of books, national and foreign journals, theses and dissertations, and scientific papers published by the faculty and researchers of the Campus.

In addition to the main titles of Neurosciences, Medicine, and Biology, researchers of the program and the community can consult the USP collection, through the Integrated Search Portal (PBi) and the bibliographic database of USP (Dédalus).

BCRP offers users online catalogs, internet access, CD-ROM databases, Multimedia Room, pro-Student Room, individual study rooms, and free guidance on the standardization of scientific papers (dissertations, theses, publications) based on the Brazilian Association of Technical Standards (ABNT).

The Library also offers online systems:

*COMUT: copies of national and international scientific papers that do not exist in the library collection;

*TURNITIN: aims to identify the similarity of texts in Portuguese and English to avoid plagiarism.

In partnership with FAPESP, researchers can also access the bibliography storage systems Medline, Lilax, Citation Index, and others, in addition to full texts in important journals (before the printed journal distribution), such as the Proceedings of the New York Academy of Sciences.

Rapid access to texts not contained in the BCRP is possible due to partnerships among SIBiUSP national and international institutions and associations for technical cooperation (http://www.aguia.usp.br/sobre/convenios-e-parceiras/).

It is possible to access the CAPES Portal for electronic journals from any computer located in the laboratory facilities, in the study and professors’ rooms. This access can also be made from the homes of professors and students via VPN.

Computer Science

Our students rely on computers in the laboratories/facilities/rooms of the professors where they develop the research activities, all connected to the computer network USPnet and internet.

The program has rooms and laboratories equipped with high-resolution multimedia projectors, cameras, and microphones for web conferences, allowing dissertation and thesis defenses, in addition to courses, lectures, etc., enabling the attendance of international guests.

Students and researchers use these data from the HCFMRP information systems, managed by the Information and Analysis Center with two data centers (Data Center).

Our researchers have the resources offered by FMRP/USP through the Technical Section of Informatics (STI-FMRP), which provides the FMRP community with a WEB server with the application REDCap (Research Electronic Data Capture) that is a free app that allows the construction and online management of “surveys” and databases aimed at clinical research.

STI-FMRP uses USP cloud resources with two SAP/Sybase Ase database servers, one Oracle MySQL, one webserver (LAMP), one Virtual Storage Server (OwnCloud), and one proxy WebServer.

The E-disciplines or Moodle of USP is a virtual learning environment whose audio and video recordings are produced by the Production Center of STI-FMRP to support the disciplines.

Faculty, students, and alumni benefit from the features that make up the G Suite for Education (Google) tool, including unlimited use of email, calendar, contact, web conferencing, file and document storage, and sharing services.

The Program also has other managed resources, such as:

*VPN: private communications network built on a Public Communication Network (Internet).

* Eduroam: a secure system developed for the international education and research community, which allows connectivity to the Internet through wireless connection (wi-fi), within its campuses and in any Venueity.

* Videoconferencing: offered to FMRP and other associated entities that make up the Academic Health Complex

* Webconference: FMRP offers, through the National Research Network-RNP, virtual rooms for meetings, classes, defenses, conferences in the Web conference mode in the Mconf software environment, from any Internet browser software.

* RUTE: the University Telemedicine Network, which aims to support the improvement of projects in telemedicine.

* SIG: RUTE encourages integration and collaboration among health professionals through GIG-Special Interest Groups. SIG’s promote sessions (remotely) for debates, case discussions, classes, research, and assessments at a distance, in various specialties.

* Official USP mobile apps, developed by STI in partnership with the various bodies of the University. STI also maintains the apps in the Apple and Google stores, performing periodic maintenance and analyzing and responding to user comments and suggestions.

Multi-user Equipment Center

The Multi-User Equipment and Services Center of the FMRP-USP has equipment and services in several segments that include images and microscopes, flow cytometers, Protein Chemistry, extraction, sequencing and amplification of DNA, among others.

See also: equipment and laboratories

Vivarium (CCCE)

Managed by the FMRP Board of Directors, the Special Mice Breeding Center (CCCE) aims to meet the demand for mice with SPF (Specific Pathogen Free) sanitary standards. It is part of the USP Vivariums Network and is also associated with the National Vivarium Network of Animal Production for Scientific, Teaching, and Technological Purposes – CNPq (REBIOTERIO).

CEUA

Duly accredited, the Committee on Ethics in the Use of Animals (CEUA-FMRP) aims to comply and enforce the creation and/or use of animals in teaching and/or research and/or training activities to ensure respect, dignity, and application of good practices recommended internationally, according to the standards of the National Council for Control of Animal Experimentation (CONCEA).

CEP

The Clinical Research Unit (UPC) provides support to researchers to ensure that research in humans carried out under the HCFMRP-USP follows national and international standards of good practices in Clinical Research (GCP/ICH).

Supported by the UPC, the Research Ethics Committee (CEP) of the HCFMRP-USP and FMRP was created to defend the interests of research subjects in their integrity and dignity, and to contribute to the development of research within ethical standards.

The research projects are sent to the CEP, through the Brazil platform, following Resolution 466/12 of the National Health Council and its complements.